一、个人情况
王明花，女，1981年10月出生，河南省徐州市人，工学博士，副教授，硕士生导师，河南省高等学校青年骨干教师。
办公地点：郑州市高新区科学大道136号，郑州轻工业大学材料与化学工程学院305房间。
E-mail: wangminghua@zzuli.edu.cn电话: 13598891032
二、教育背景
1999.09-2003.06 郑州轻工业学院，高分子材料与工程，获工学学士学位；
2003.09-2006.06 郑州轻工业学院，应用化学，获工学硕士学位；
2015.09-2018.06 河北工业大学，材料科学与工程，获工学博士学位
三、研究方向
环境功能材料、生物传感器、光催化及水污染治理
四、承担课程及教学成果
承担本科生《环境治理功能材料》、《高分子材料成型工艺》、《高分子材料》等课程和硕士研究生《智能材料》、《环境友好材料生产与应用》课程。
(1) 教育部产学合作协同育人项目, 221000650102551，基于产教融合的仿真技术创新实践师资培训，2022.11-2024.10，3万元，在研，主持；
(2)河南省高等教育教学改革研究与实践项目，2021SJGLX202，高等学校产教融合、科教融合协同创新发展研究，2022.01-2023.10，3万元，已结题，参加；
(3) 河南省教学改革项目，2014 SJGLX243，高校工科专业课程探究式教学考核体系的研究与实践，2014.01-2015.09，2万元，已结题，参加，2016.10获得河南省优秀教学成果二等奖：豫教[2016]24125号；
(4) 郑州轻工业学院第三批青年教师教学改革与研究项目，环保材料与应用课程探究式教学、考核方式的研究与实践，2014.10-2017.06，0.3万元，已结题，主持，2017.06通过校级鉴定：郑轻院青年教改鉴字（2017）039号；
(5)“挑战杯”河南省大学生创业计划竞赛铜奖，胶体金微流控纸芯片的设计及抗生素快速检测，指导老师，2020.12；
(6)河南省“互联网+”大学生创新创业大赛二等奖，“纳米”遇到“酶”新型真菌毒素速测试剂盒，指导老师，2021.10；
(7)河南省大学生创新创业训练计划优秀成果一等奖，抗生素快速检测胶体金侧流层析试纸条的研制，豫[2022]37639，指导老师，2022.11。
五、科研成果及奖励（项目、专利、奖励等）
项目：
(1) 河南省高等学校重点科研项目计划：石墨烯基多功能化水凝胶作为吸附材料在水净化中的应用研究（15A610024），2015.01-2017.12，经费2万，结项，主持；
(2)河南省科技攻关项目：MOFs@COFs基核酸适体电化学生物传感器的构筑及其在抗生素检测中的应用（192102310261），2019.01-2020.12，经费10万，结项，主持；
(3) 河南省高等学校青年骨干教师培养计划：金属-有机骨架复合材料的合成及其传感性能研究（2018GGJS089），2019.02-2022.06，经费6万，结项，主持；
(4) 企业横向项目：多孔碳基生物功能材料的制备开发（CLY20190069），2019.05-2021.03，经费35万，结项，主持；
(5) 河南省科技攻关项目：双功能MOFs基电/光电化学生物传感器构建及食品中抗生素快速检测（222102310153），2022.01-2023.12，经费10万，结项，主持。
专利：
(1) 一种石墨烯/壳聚糖/氧化亚铜复合材料及其制备方法和应用，国家发明专利，专利号ZL 201410811364.8，2017.06.16；
(2)一种Cu3P@Ti-MOF-NH2复合材料、电化学传感器及其制备方法和应用，国家发明专利，专利号：ZL201711407710.6，2020.01.03；
(3) 适体传感器用电极材料、适体传感器及其制备方法，国家发明专利，专利号：ZL201910641407.5，2021.08.27；
(4) 双金属-有机骨架材料、支架材料及其制备方法，电化学免疫传感器及其制备方法、应用，国家发明专利，专利号：ZL201910190047.1，2021.11.09；
(5) 一种镍钴氧化物/石墨烯纳米杂化材料及其应用和电化学传感器，国家发明专利，专利号：ZL201910935216.X，2022.04.12。
获奖情况：
(1) 新型生物传感器敏感膜材料构筑的关键技术及应用，河南省科技进步二等奖， 2019-J-071-R03/10，2020.01；
(2) 石墨烯基等离子体复合材料作为重金属离子检测方面的应用技术，河南省教育厅科技成果一等奖，豫教[2016]01552， 2016.05；
(3) 等离子体聚丙烯胺在蛋白质检测方面的应用技术，河南省教育厅科技成果二等奖，豫教[2016]01687， 2016.05；
(4) 锆基多孔纳米材料在生物传感方面的应用技术，河南省教育厅科技成果二等奖，豫教[2019]01654，2019.05；
(5) Graphene nanostructures with plasma polymerized allylamine biosensor for selective detection of mercury ions，河南省自然科学优秀学术论文三等奖，2015.12；
(6) Electrochemical biosensor based on Cu/Cu2O nanocrystals and reduced graphene oxide nanocomposite for sensitively detecting ractopamine，河南省自然科学优秀学术论文二等奖，2018.01；
(7) Bimetallic metal–organic framework derived FeOx/TiO2 embedded in mesoporous carbon nanocomposite for the sensitive electrochemical detection of 4-nitrophenol，河南省自然科学优秀学术论文二等奖，2021.12。
发表论著（著作、发表文章等）
(1) Minghua Wang, Shunli Liu, Yuanchang Zhang, Yanqin Yang, Yu Shi, Linghao He, Shaoming Fang, Zhihong Zhang*. Graphene nanostructures with plasma polymerized allylamine biosensor for selective detection of mercury ions. Sensors & Actuators B. Chemical, 2014, 203, 497-503.(一区)
(2) Minghua Wang, Mengmeng Kang, Chuanpan Guo, Shaoming Fang, Linghao He, Chunxiao Jia, Gaihong Zhang, Bing Bai, Wei Zong, Zhihong Zhang*, Electrochemical biosensor based on Cu/Cu2O nanocrystals and reduced graphene oxide nanocomposite for sensitively detecting ractopamine.Electrochimica Acta, 2015,182,668-675.(二区)
(3) Minghua Wang, Shuyong Zhai, Linghao He, Donglai Peng, Xiaozhong Feng, Yanqin Yang, Shaoming Fang, Hongzhong Zhang*, Zhihong Zhang*, An electrochemical aptasensor based on TiO2/three-dimensional reduced graphene oxide/PPy nanocomposite for the sensitive detection of lysozyme. Dalton Transactions, 2015, 44(14): 6473-6479.(二区)
(4) Minghua Wang, Shuai Zhang, Zihan Ye, Donglai Peng, Linghao He, Fufeng Yan, Yanqin Yang, Hongzhong Zhang, Zhihong Zhang*. A gold electrode modified with amino-modified reduced graphene oxide, ion specific DNA and DNAzyme for dual electrochemical determination of Pb (II) and Hg (II). Microchimica Acta, 2015, 182(13-14): 2251-2258.(二区)
(5) Minghua Wang, Lifang Cai, Qingxian Jin, Hongzhong Zhang, Shaoming Fang, Xiongwei Qu, Zhihong Zhang*, Qingxin Zhang*, One-pot composite synthesis of three-dimensional graphene oxide/poly (vinyl alcohol)/TiO2 microspheres for organic dye removal, Separation and Purification Technology, 2017, 172, 217–226.(一区)
(6) Minghua Wang, Bin Hu, Hongfei Ji, Yingpan Song, Jiameng Liu, Donglai Peng, Linghao He,Zhihong Zhang*. Aptasensor Based on Hierarchical Core−Shell Nanocomposites ofZirconium Hexacyanoferrate Nanoparticles and MesoporousmFe3O4@mC: Electrochemical Quantitation of Epithelial TumorMarker Mucin 1. ACS Omega, 2017, 2, 6809-6818.
(7) Minghua Wang, Bin Hu, Chuang Yang, Zhihong Zhang*, Linghao He, Shaoming Fang, Xiongwei Qu, Qingxin Zhang, Electrochemical biosensing based on protein-directed carbon nanospheres embedded with SnOx and TiO2 nanocrystals for sensitive detection of tobramycin. Biosensors and Bioelectronics, 2018, 99, 176–185.(一区)
(8) Minghua Wang, Longyu Yang, Bin Hu, Yongkang Liu, Yingpan Song, Linghao He, Zhihong Zhang*,Shaoming Fang*. A novel electrochemical sensor based on Cu3P@NH2-MIL-125(Ti)nanocomposite for efficient electrocatalytic oxidation and sensitivedetection of hydrazine. Applied Surface Science, 2018, 445,123–132.(一区)
(9) Minghua Wang, Longyu Yang, Jinyun Yuan, Linghao He, Yingpan Song, Hongzhong Zhang, Zhihong Zhang*, Shaoming Fang*. Heterostructured Bi2S3@NH2-MIL-125(Ti) nanocomposite as a bifunctional photocatalyst for Cr(VI) reduction and rhodamine B degradation under visible light. RSC Advances, 2018, 8, 12459–12470.
(10) Wang Minghua, Yang Longyu, Guo Chuanpan, Liu Xufei, He Linghao, Song Yingpan, Zhang Qingxin, Qu Xiongwei*, Zhang Hongzhong, Zhang Zhihong*, Fang Shaoming*. Bimetallic Fe/Ti-based metal–organic framework for persulfate-assisted visible light photocatalytic degradation of Orange II.ChemistrySelect, 2018, 3, 3664–3674.
(11) Wang Minghua, Yang Longyu, Hu Bin, Liu Jiameng, He Linghao, Jia Qiaojuan, Song Yingpan, Zhang Zhihong. Bimetallic NiFe oxide structures derived from hollow NiFe Prussian blue nanobox for label-free electrochemical biosensing adenosine triphosphate. Biosensors and Bioelectronics, 2018, 113, 16–24. (一区，ESI高被引论文)
(12) Minghua Wang, Yongkang Liu, Longyu Yang, Kuan Tian, Linghao He,Zhihong Zhang*,Qiaojuan Jia, Yingpan Song, Shaoming Fang*. Bimetallic metal–organic framework derived FeOx/TiO2embedded inmesoporous carbon nanocomposite for the sensitive electrochemicaldetection of 4-nitrophenol. Sensors and Actuators B: Chemical，2019, 281, 1063-1072. (一区)
(13) Minghua Wang, Mengyao Hu, Jiameng Liu, Chuanpan Guo, Donglai Peng, Qiaojuan Jia,Linghao He, Zhihong Zhang*, Miao Du*, Covalent organic framework-based electrochemical aptasensors for theultrasensitive detection of antibiotics.Biosensors and Bioelectronics,2019, 132, 8-16. (一区，ESI高被引论文)
(14) Minghua Wang, Mengyao Hu, Bin Hu, Chuanpan Guo, Yingpan Song, Qiaojuan Jia, Linghao He, Zhihong Zhang∗, Shaoming Fang∗∗. Bimetallic cerium and ferric oxides nanoparticles embedded within mesoporous carbon matrix: Electrochemical immunosensor for sensitive detection of carbohydrate antigen 19-9. Biosensors and Bioelectronics, 2019, 135, 22–29. (一区，ESI热点、高被引论文)
(15) Minghua Wang, Mengyao Hu, Zhenzhen Li, Linghao He, Yingpan Song, Qiaojuan Jia,Zhihong Zhang*, Miao Du. Construction of Tb-MOF-on-Fe-MOF conjugate as a novel platform for ultrasensitive detection of carbohydrate antigen 125 and living cancer cells. Biosensors and Bioelectronics, 2019, 142: 111536.(一区，ESI热点、高被引论文)
(16) Minghua Wang, Changbao Wang, Yongkang Liu, Bin Hu, Linghao He, Yashen Ma, Zhihong Zhang*, Bingbing Cui, Miao Du, Nonenzymatic amperometric sensor for hydrogen peroxide released from living cancer cells based on hierarchical NiCo2O4-CoNiO2 hybrids embedded in partially reduced graphene oxide. Microchimica Acta, 2020, 187, 1-14. (二区)
(17) Minghua Wang, Changbao Wang, Lei Zhu, Feilong Rong, Linghao He, Yafei Lou, Zhihong Zhang*. Bimetallic NiCo metal-organic frameworks for efficient non-Pt methanol electrocatalytic oxidation. Applied Catalysis A: General, 2021, 619, 118159.(二区)
(18) Minghua Wang, Lei Zhu, Shuai Zhang, Yafei Lou, Shuangrun Zhao, Quan Tan, Linghao He, Miao Du*. A copper (II) phthalocyanine-based metallo-covalent organic framework decorated with silver nanoparticle for sensitively detecting nitric oxide released from cancer cells. Sensors and Actuators B: Chemical, 2021, 338, 129826. (一区)
(19) Minghua Wang, Changbao Wang, Jiameng Liu, Feilong Rong, Linghao He, Yafei Lou, Zhihong Zhang*, Miao Du*, Efficient Ag/Ag2O-Doped Cobalt Metallo-Covalent Organic Framework Electrocatalysts for Rechargeable Zinc-Air Battery. ACS Sustainable Chemistry & Engineering, 2021, 9(17), 5872-5883. (一区)
(20) Minghua Wang, Gaolei Liang, Mengfei Wang, Min Hu, Lei Zhu, Zhenzhen Li, Zhihong Zhang*, Linghao He, Miao Du*. Electroactive and photoactive porphyrin-based covalent-organic framework for the construction of a bifunctional self-powered sensing platform toward real time analysis of nitride oxide from cancer cells. Chemical Engineering Journal, 2022, 448, 137779. (一区，IF=16.7)
(21) Fufeng Yan, Lijun Hu, Minghua Wang*, Shunjiang Huang, Shuai Zhang, Linghao He, Zhihong Zhang*, Multifunctional photocatalyst of graphitic carbon embedded with Fe2O3/Fe3O4 nanocrystals derived from lichen for efficient photodegradation of tetracycline and methyl blue. Environmental Technology, DOI: 10.1080/09593330.2022.2164522.
(22) Jing Cui, Baiwei Wu, Zhenzhen Li, Yanhong Bai, Lun Kan, Minghua Wang*, Linghao He, Miao Du*, Hierarchical CoCoPBA@PCN-221 nanostructure for the highly sensitive detection of deoxynivalenol in foodstuffs. Food Chemistry, 2023, 403, 134370. (一区)
(23) Li Ma, Kaige Chen, Hao Dang, Minghua Wang*. Establishment of a photoactive heterojunction of triazine covalent-organic polymer and copper (II) selenide: Photoelectrochemical aptasensing strategy for efficiently detecting Salmonella typhimurium. Microchemical Journal, 2023, 193: 109162. (二区)
(24) Miaoran Xu, Hao Dang, Mengfei Wang, Shuai Zhang, Qiaojuan Jia, Jia-Yue Tian, Minghua Wang*, Miao Du*. New dual-modal electrochemical and photoelectrochemical aptasensing strategy for the sensitive detection of penicillin G based on an iron-doped covalent triazine framework. Microchemical Journal, 2023, 194: 109242. (二区)
(25) Minghua Wang, Mengfei Wang, Shunjiang Huang, Shuai Zhang, Zhihong Zhang*, Linghao He, Miao Du*, Confinement of defect-rich bimetallic In2O3/CeO2 nanocrystals in mesoporous nitrogen-doped carbon as a sensitive platform for photoelectrochemical aptasensing of Escherichia coli. Analytica Chimica Acta, 2023,1248, 340893.(一区)
(26)《功能高分子材料》，华中科技大学出版社，ISBN：978-7-5680-2098-5，主编，2016.06
(27)《环境友好型高分子材料的制备与应用》，吉林出版集团股份有限公司，ISBN：978-7-5731-0329-1，独著，2021.08
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